Reddy, current Vice-President M. Venkaiah Naidu and late Gouthu Latchanna had served as a strong Oppositon in the State Assembly.
He was Union Minister for Information and Broadcasting, Union Minister for Urban Development, Union Minister for Petroleum and Natural Gas before finally holding the subject of science technology.
Reddy was admitted to the Asian Institute of Gastroenterology in Gachibowli with a high fever a few days back, and was undergoing treatment.
Reddy joined politics as a student leader of Osmania University annd went on to become Congress MLA in 1970s .
He was Rajya Sabha member from 1990 to 1996 and became Leader of Opposition in the Upper House in 1991-1992.